Tania Wang

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Email: i at tania.wang

View the Project on GitHub xigyou/tania.github.io

Welcome

Hi! I am Tania Wang, Welcome to my personal website.

Work Experience

2019.03 - 2019.08 Beijing Institutes of Life Science, CAS

2019.03 - 2019.08   Bioinformatics Engineer

2014.07 - 2019.02 AccuraScience, LLC

2015.05 - 2019.02   Project Supervisor

2014.07 - 2015.05   Bioinformatics Engineer

Project Experience and Capabilities

  1. Experienced skills in Next-Generation sequencing (Illumina) data analysis including genomics, transcriptome and regulatome (miRNA, ncRNA, ChIP-seq on histone marks and epigenome).
  2. Experienced skills in gene expression microarray analysis.
  3. Experienced skills in machine learning applications on identification of gene expression signatures using four classification methods including support vector machine (SVM), random forest (RF), Naïve Bayes (NB) and Linear Discriminant Analysis (LDA), and four feature selection methods including recursive feature elimination (RFE), Chi-Squared (CS), correlation-based feature selection method (CFS) and information gain ratio (IGR).
  4. Highly skilled in Perl programming: seven years.
  5. Considerably experienced in R Statistical and Linux Shell Programming.
  6. Familiar with Python, PHP, SQL and JavaScript Language.

Education

2019.09 - now: Ph.D, School of Life Sciences, CSU, Changsha, P. R. China, Genetics.

2019.09 - now: Ph.D, Beijing Institutes of Life Science, CAS, Beijing, P. R. China, Genetics.

2011.09 - 2014.06: M.S., Wenzhou Medical University, Wenzhou, P. R. China, Genetics.

2006.09 - 2010.06: B.S., Chongqing University of Posts and Telecommunications, Chongqing, P. R. China, Bioinformatics.

Publications

  1. Wang T, Zhang Y, Liu L, Wang Y, Chen H, Fan T, Li J, Xia K, Sun Z. Targeted sequencing and integrative analysis of 3,195 Chinese patients with neurodevelopmental disorders prioritized 26 novel candidate genes. J GENET GENOMICS. 2021 Apr 20;48(4):312-323. doi: 10.1016/j.jgg.2021.03.002. Epub 2021 Apr 1. PMID: 33994118. pdf download
  2. Zhang Y, Wang T, Wang Y, Xia K, Li J, Sun Z. Targeted sequencing and integrative analysis to prioritize candidate genes in neurodevelopmental disorders. Mol Neurobiol. 2021 Apr 15. doi: 10.1007/s12035-021-02377-y. Epub 2021 Apr 15. PMID: 33860439; PMCID: PMC8280036. pdf download
  3. Wang T, Ruan S, Zhao X, Shi X, Teng H, Zhong J, You M, Xia K, Sun Z, Mao F. OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancers. Nucleic Acids Res. 2021 Jan 8;49(D1):D1289-D1301. doi: 10.1093/nar/gkaa1033. PMID: 33179738; PMCID: PMC7778899. pdf download
  4. Li QS, Sun Y, Wang T. Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regions. Clin Epigenetics. 2020 Oct 17;12(1):149. doi: 10.1186/s13148-020-00944-z. PMID: 33069246; PMCID: PMC7568396. pdf download
  5. Wang H, Wang T, Zhao X, Wu H, You M, Sun Z, Mao F. AI-Driver: an ensemble method for identifying driver mutations in personal cancer genomes. NAR Genom Bioinform. 2020 Oct 13;2(4):lqaa084. doi: 10.1093/nargab/lqaa084. PMID: 33575629; PMCID: PMC7671397. pdf download
  6. Robakis TK, Zhang S, Rasgon NL, Li T, Wang T, Roth MC, Humphreys KL, Gotlib IH, Ho M, Khechaduri A, Watson K, Roat-Shumway S, Budhan VV, Davis KN, Crowe SD, Ellie Williams K, Urban AE. Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Transl Psychiatry. 2020 Feb 3;10(1):48. doi: 10.1038/s41398-020-0703-3. PMID: 32066670; PMCID: PMC7026105. pdf download
  7. Wu J, Yu P, Jin X, Xu X, Li J, Li Z, Wang M, Wang T, Wu X, Jiang Y, Cai W, Mei J, Min Q, Xu Q, Zhou B, Guo H, Wang P, Zhou W, Hu Z, Li Y, Cai T, Wang Y, Xia K, Jiang YH, Sun ZS. Genomic landscapes of Chinese sporadic autism spectrum disorders revealed by whole-genome sequencing. J Genet Genomics. 2018 Oct 20;45(10):527-538. doi: 10.1016/j.jgg.2018.09.002. Epub 2018 Oct 21. PMID: 30392784. pdf download
  8. Li J, Jiang Y, Wang T, Chen H, Xie Q, Shao Q, Ran X, Xia K, Sun ZS, Wu J. mirTrios: an integrated pipeline for detection of de novo and rare inherited mutations from trios-based next-generation sequencing. J Med Genet. 2015 Apr;52(4):275-81. doi: 10.1136/jmedgenet-2014-102656. Epub 2015 Jan 16. PMID: 25596308. pdf download
  9. Wang T, Liu Q, Li X, Wang X, Li J, Zhu X, Sun ZS, Wu J. RRBS-analyser: a comprehensive web server for reduced representation bisulfite sequencing data analysis. Hum Mutat. 2013 Dec;34(12):1606-10. doi: 10.1002/humu.22444. Epub 2013 Oct 10. PMID: 24106010. pdf download
  10. Wang M, Fan X, Wang T, Wu J. High-throughput sequencing of autism spectrum disorders comes of age. Genet Res (Camb). 2013 Aug;95(4):121-9. doi: 10.1017/S0016672313000153. PMID: 24074369. pdf download
  11. Teng H, Cai W, Zeng K, Mao F, You M, Wang T, Zhao F, Sun Z. Genome-wide identification and divergent transcriptional expression of StAR-related lipid transfer (START) genes in teleosts. Gene. 2013 Apr 25;519(1):18-25. doi: 10.1016/j.gene.2013.01.058. Epub 2013 Feb 13. PMID: 23415839. pdf download
  12. Wu J, Liu Q, Wang X, Zheng J, Wang T, You M, Sheng Sun Z, Shi Q. mirTools 2.0 for non-coding RNA discovery, profiling, and functional annotation based on high-throughput sequencing. RNA Biol. 2013 Jul;10(7):1087-92. doi: 10.4161/rna.25193. Epub 2013 May 29. PMID: 23778453; PMCID: PMC3849156. pdf download